Biochemical, Hematological and Histological Changes in a Fulminant HeDatic Failure Rat Model for Ahificial Liver Assessment

Abstract
Galactosamine-induced fulminant hepatic failure rats were used as a model for statistical assessment of liver support systems. The biochemical, hematological and histological changes in these animals are reported in detail. They were used to study statistically the effects of charcoal hemoperfusion, cross-circulation and liver perfusion on long-term survival in fulminant hepatic failure.