NADPH:O2 oxidoreductase of human eosinophils in the cell‐free system
- 30 July 1990
- journal article
- Published by Wiley in FEBS Letters
- Vol. 268 (1), 269-273
- https://doi.org/10.1016/0014-5793(90)81025-j
Abstract
The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neutrophils. Eosinophils isolated from patients with chronic granulomatous disease show the same molecular defects as the neutrophils fom these patients.Keywords
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