Preparation of single, soluble antigens of the mouse histocompatibility-2 complex.
- 1 May 1967
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 57 (5), 1226-1231
- https://doi.org/10.1073/pnas.57.5.1226
Abstract
Tryptic digestion of insoluble mouse tissue stoma, followed by treatment with a chelating agent, releases specific inhibitors of anti-Histocompatibility-2 cytoxic alloantisera, presumably complexes of H-2 antigenic determinants. These inhibitors may be purified by isolation from antigen-antibody complexes, and may be resolved into single antigens by further proteolysis followed by a 2nd isolation using monospecific antisera.This publication has 7 references indexed in Scilit:
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