An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney
Open Access
- 18 September 2008
- journal article
- research article
- Published by Springer Nature in BMC Developmental Biology
- Vol. 8 (1), 86
- https://doi.org/10.1186/1471-213x-8-86
Abstract
Bone morphogenetic proteins (BMPs) regulate essential processes during organogenesis, and a functional understanding of these secreted proteins depends on identification of their target cells. In this study, we generate a transgenic reporter for organogenesis studies that we use to define BMP pathway activation in the developing kidney.Keywords
This publication has 74 references indexed in Scilit:
- Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence FactorCirculation Research, 2008
- Bmp in Podocytes Is Essential for Normal Glomerular Capillary FormationJournal of the American Society of Nephrology, 2008
- BMP signaling in dermal papilla cells is required for their hair follicle-inductive propertiesGenes & Development, 2008
- BMP Receptor ALK3 Controls Collecting System DevelopmentJournal of the American Society of Nephrology, 2008
- Conditional Deletion of Smad1 and Smad5 in Somatic Cells of Male and Female Gonads Leads to Metastatic Tumor Development in MiceMolecular and Cellular Biology, 2008
- Control of kidney, eye and limb expression of Bmp7 by an enhancer element highly conserved between speciesDevelopmental Biology, 2007
- In vivo enhancer analysis of human conserved non-coding sequencesNature, 2006
- Genetic Analysis of the Roles of BMP2, BMP4, and BMP7 in Limb Patterning and SkeletogenesisPLoS Genetics, 2006
- BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning.Genes & Development, 1995
- A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.Genes & Development, 1995