Serum lipids and hippocampal volume: The link to Alzheimer's disease?
- 25 October 2004
- journal article
- research article
- Published by Wiley in Annals of Neurology
- Vol. 56 (5), 745-749
- https://doi.org/10.1002/ana.20289
Abstract
The association between hippocampal volume (as a presumed index of Alzheimer's disease pathology) with serum total cholesterol, high‐density lipoprotein cholesterol, and low‐density lipoprotein cholesterol was studied in 86 elderly subjects with a range of cognitive functions. High‐density lipoprotein cholesterol, but not low‐density lipoprotein cholesterol or total cholesterol, was associated with hippocampal volume and dementia. This is compatible with protective effects of high‐density lipoprotein cholesterol on hippocampal atrophy and Alzheimer's disease. Ann Neurol 2004;56:745–749Keywords
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