Myocardial Oxygen Consumption, Left Ventricular Fibre Shortening and Wall Tension

Abstract
Myocardial oxygen consumption (MVO2) was studied in a canine right heart bypass preparation. At constant heart rate and left ventricular peak developed tension (calculated from ventricular volume and pressure), doubling cardiac inflow increased MVO2 by 1·3 ml./100 g LV/min. This approximate 10% increase is attributed to increased contractile element shortening and work.

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