Cytotoxic Diterpenes from the Rhizomes ofHedychium coronarium

Abstract
Four new labdane-type diterpenes, coronarin, A, B, C, and D, and one known labdane-type diterpene, (E)-labda-8(17), 12- diene-15, 16-dial were isolated as cytotoxic prinicples from the rhizomes of Hedychium coronarium, Zingiberaceae. The structures were established by chemical and spectroscopic methods.