The release of chlorhexidine from modified dental acrylic resin
- 1 May 1993
- journal article
- Published by Wiley in Journal of Oral Rehabilitation
- Vol. 20 (3), 311-319
- https://doi.org/10.1111/j.1365-2842.1993.tb01613.x
Abstract
A method for the incorporation of chlorhexidine into acrylic resin using monomer together with the pattern of release of chlorhexidine from treated resin into water at 37 degrees C is described. Release from polished and unpolished resin, and from acrylic prepared by short-curing and dry-curing processes are investigated. The pattern of release in all cases was of an exponential nature, showing a rapid release within the first 10 days becoming almost constant at a level of 0.4-1.5 micrograms cm-2 at about 20 days. Release was still evident at the end of the test period in all cases. Release of chlorhexidine into water from the short-cure specimens was accompanied by release of monomer, evident from the odour of the test solutions, indicating that polymerization was not complete.Keywords
This publication has 16 references indexed in Scilit:
- The Use of 0.2% Chlorhexidine Spray as an Adjunct to Oral Hygiene and Gingival Health in Physically and Mentally Handicapped AdultsThe Journal of Periodontology, 1989
- Comparison of Chlorhexidine Delivery by Mouthwash and Spray on Plaque AccumulationThe Journal of Periodontology, 1989
- Prevention of plaque growth with chewing gum containing chlorhexidine acetateJournal of Clinical Periodontology, 1987
- Comparison of Two Routines for Long-Term Oral Hygiene Treatment with Chlorhexidine Gel in Geriatric Patients1Gerodontology, 1987
- Development of Sustained-release Antimicrobial Dental Varnishes Effective Against Streptococcus mutans in vitroJournal of Dental Research, 1985
- New sustained release dosage form of chlorhexidine for dental useJournal of Periodontal Research, 1982
- The Effect of A 1% Chlorhexidine Gel in the Initial Therapy of Chronic Periodontal DiseaseThe Journal of Periodontology, 1978
- Influence of teeth, plaque and dentures on the retention of chlorhexidine in the human oral cavityJournal of Clinical Periodontology, 1974
- The effect of mouthrinses and topical application of chlorhexidine on the development of dental plaque and gingivitis in manJournal of Periodontal Research, 1970
- The absorption of water by acrylic resins and other materialsThe Journal of Prosthetic Dentistry, 1964