GAMMA-MELANOTROPIN IS NOT PRESENT IN AN N-TERMINAL PEPTIDE OF SALMON PROOPIOCORTIN

Abstract
The N-terminal peptide of salmon proopiocortin was isolated and the primary structure including 2 disulfide bonds elucidated. The peptide consisted of 76 amino acid residues, which is 27 residues shorter than the bovine and human peptides. The N-terminal 44 residues of the teleost peptide exhibited significant sequence homology to those of the mammalian peptides. The salmon peptide, however, is lacking in the counterpart of .gamma.-MSH which is located between residues 51 and 64 in the mammalian peptides.