Lanthanide-ion transport across phospholipid vesicular membranes: a comparison of alamethicin 30 and A23187 using 1H-NMR spectroscopy
Open Access
- 1 November 1982
- journal article
- research article
- Published by Portland Press Ltd. in Bioscience Reports
- Vol. 2 (11), 921-928
- https://doi.org/10.1007/bf01114899
Abstract
The kinetics of Pr3+ transport by the ionophores alamethicin 30 and A23187 across unilamellar phospho-lipid vesicular membranes has been compared by following the time-dependent changes in the 1H-NMR spectrum of the vesicles. The measured rates of transport allow stoichiometries of the transporting species to be deduced which are consistent with channel- and carrier-mediated mechanisms respectively. The method provides a useful complement to planar bilayer conductivity studies of these systems.This publication has 28 references indexed in Scilit:
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