Norepinephrine Stimulated Increase of Cyclic AMP Levels in Developing Mouse Brain Cell Cultures
- 15 October 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 174 (4006), 292
- https://doi.org/10.1126/science.174.4006.292
Abstract
Norepinephrine causes a four- to sixfold increase in the intracellular level of cyclic AMP (adenosine 3', 5'-monophosphate) reaggregated brain cell cultures derived from embryonic mouse brain. The cyclic AMP level of adult brain is increased by norepinephrine; however, embryonic mouse brain does not show a cyclic AMP response. The aggregate cultures thus demonstrate an event of differentiation very similar to that seen in vivo.Keywords
This publication has 5 references indexed in Scilit:
- Biochemical Differentiation in Reaggregating Brain Cell CultureProceedings of the National Academy of Sciences, 1971
- A Protein Binding Assay for Adenosine 3′:5′-Cyclic MonophosphateProceedings of the National Academy of Sciences, 1970
- Histogenesis of fetal mouse isocortex and hippocampus in reaggregating cell culturesDevelopmental Biology, 1970
- Cyclic AMP and adenyl cyclase in the developing rat brainDevelopmental Psychobiology, 1970
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951