Light and electron microscopy study of capillaries in normal and inflammatory human synovial membrane.
Open Access
- 1 June 1977
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 30 (6), 556-562
- https://doi.org/10.1136/jcp.30.6.556
Abstract
Synovium aspirated from the knee joint by trochar was studied by light and electron microscopy in 40 cases of inflammatory arthritis and in 10 controls. The morphology of synovial capillaries, extravascular plasma diffusion, interendothelial vascular gaps, extracapillary blood cell migration, vascular congestion, endothelial hyperplasia, and obliteration of the capillary lumen by endothelial cells were compared in normal and inflammatory synovia. Inflammatory synovitis was characterised by the number and diversity of blood cells migrating through the interendothelial pathway out of the capillary lumen. Polymorphonuclear leucocytes were the blood cells most often seen at interendothelial junctions. No other capillary changes that might be related to synovial inflammation were found.Keywords
This publication has 17 references indexed in Scilit:
- Electron Microscopic Studies of Lymphoid Cells in the Rheumatoid Synovial MembraneArthritis & Rheumatism, 1973
- Synovitis of recent onset. A clinicopathologic study during the first month of diseaseArthritis & Rheumatism, 1972
- Tubular paramyxovirus-like structures in synovial vascular endothelium.Annals Of The Rheumatic Diseases, 1970
- The microvasculature of the synovial membrane of the monkey: Ultrastructural studiesArthritis & Rheumatism, 1969
- Systemic Lupus Erythematosus and MyxovirusNew England Journal of Medicine, 1969
- To the Question of Angiopathy in Rheumatoid Arthritis:An Electron Microscopic StudyActa Orthopaedica, 1969
- Ultrastructure of synovial membrane in rheumatoid arthritis.Annals Of The Rheumatic Diseases, 1967
- Light and electron microscopic observations on the synovitis of reiter's diseaseArthritis & Rheumatism, 1966
- Electron microscopic observations on the rheumatoid synovial membraneArthritis & Rheumatism, 1966
- STUDIES ON INFLAMMATIONThe Journal of cell biology, 1961