THE EFFECT OF ANOXIA ON THE ABSORPTION OF GLUCOSE AND OF GLYCINE FROM THE SMALL INTESTINE

Abstract

Barbitalized dogs were used for these expts. The same technique was used as that reported in previous studies of the effect of anoxia on absorption. Partial pressures of O2 used were, 117, 94, 80, 63 and 53 mm. Hg, corresponding to approx. altitudes of 8,000, 14,000, 18,000, 24,000 and 28,000 ft. respectively. Anoxia up to and including 53 mm. Hg partial pressure of O2 did not alter significantly the absorption of glucose from the small intestine. The absorption of glycine, however, was significantly depressed at 53 mm. Hg O2 tension, but not higher pressures. The expts. suggested that possibly an oxidative process is directly involved in absorption of glycine.