The separation and purification of rat liver UDP-glucuronyltransferase activities towards testosterone and oestrone
- 1 August 1980
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 189 (2), 377-380
- https://doi.org/10.1042/bj1890377
Abstract
1. Reconstitution of UDP-glucuronyltransferase preparations with phosphataidylcholine liposomes facilitated the purification of testosterone UDP-glucuronyltransferase. 2. Transferase activity towards testosterone co-purifies with that towards 4-nitrophenol. 3. UDP-glucuronyltransferase activity towards oestrone was separated from that towards testosterone. 4. These results suggest that testosterone and 4-nitrophenol may be glucuronidated by a different form of UDP-glucuronyltransferase from the one glucuronidating oestrone.This publication has 17 references indexed in Scilit:
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