The fatty meal test: an alternative to stool fat analysis
Open Access
- 1 November 1983
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 38 (5), 763-768
- https://doi.org/10.1093/ajcn/38.5.763
Abstract
In view of the technical difficulties inherent in using stool fat estimations as a parameter of malabsorption, we used a fatty meal absorption test. Children under investigation for failure to thrive were divided into two groups, those having a normal stool fat output (less than 3.2 g/day) constituting the control group, and those having steatorrhea. After a fatty meal containing 25 g of margarine and 25 g of butter fat, we measured the rise of serum triglycerides and chylomicrons hourly for 5 h. Serum triglyceride rise of less than 100 mg/dl or less than 100% above basal values and the appearance of less than 7% of chylomicrons were considered pathological. Of our control group 95% had a normal rise of triglycerides, and 96% of our patients with steatorrhea had an abnormal rise. This test was more reliable than the two-point triglyceride test previously described for the diagnosis of fat malabsorption. The fatty meal test as described here is considered to be a useful test of absorptive function.This publication has 18 references indexed in Scilit:
- Reversal of Biochemical and Functional Abnormalities in Erythrocytes Secondary to Selenium DeficiencyJournal of Parenteral and Enteral Nutrition, 1983
- An Occidental Case of Cardiomyopathy and Selenium DeficiencyNew England Journal of Medicine, 1981
- Trace Element Balance in Adults Receiving Parenteral Nutrition: Preliminary DataJournal of Parenteral and Enteral Nutrition, 1981
- Protection of Human Neutrophils by Endogenous CatalaseJCI Insight, 1980
- Oxidative Damage to Neutrophils in Glutathione Synthetase DeficiencyBritish Journal of Haematology, 1979
- Oxygen-Dependent Microbial Killing by PhagocytesNew England Journal of Medicine, 1978
- Balance study of twenty trace elements during total parenteral nutrition in manBritish Journal of Nutrition, 1977
- Glutathione Peroxidase, V. The kinetic mechanismHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1972
- METABOLIC AND MORPHOLOGICAL OBSERVATIONS ON THE EFFECT OF SURFACE-ACTIVE AGENTS ON LEUKOCYTESThe Journal of cell biology, 1967
- Glutathione Peroxidase: The Primary Agent for the Elimination of Hydrogen Peroxide in Erythrocytes*Biochemistry, 1963