Small molecules affecting transcription in Friedreich ataxia
- 9 August 2007
- journal article
- review article
- Published by Elsevier in Pharmacology & Therapeutics
- Vol. 116 (2), 236-248
- https://doi.org/10.1016/j.pharmthera.2007.06.014
Abstract
No abstract availableKeywords
This publication has 82 references indexed in Scilit:
- Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genesProceedings of the National Academy of Sciences, 2007
- Repeat-induced epigenetic changes in intron 1 of the frataxin gene and its consequences in Friedreich ataxiaNucleic Acids Research, 2007
- Effects of Friedreich's ataxia (GAA)n{middle dot}(TTC)n repeats on RNA synthesis and stabilityNucleic Acids Research, 2007
- Mitochondrial protein import and human health and diseaseBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2006
- Rational selection of small molecules that increase transcription through the GAA repeats found in Friedreich's ataxiaFEBS Letters, 2006
- GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathologyGenomics, 2006
- DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA·TTC repeats in Friedreich's ataxiaProceedings of the National Academy of Sciences, 2006
- Displacement of D1, HP1 and topoisomerase II from satellite heterochromatin by a specific polyamideThe EMBO Journal, 2006
- The Structure and Function of FrataxinCritical Reviews in Biochemistry and Molecular Biology, 2006
- The language of covalent histone modificationsNature, 2000