TERATOGENIC EFFECT OF MATERNAL ALCOHOL CONSUMPTION ON THE MOUSE FETUS
- 1 July 1980
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section A Pathology
- Vol. 88A (1-6), 285-289
- https://doi.org/10.1111/j.1699-0463.1980.tb02498.x
Abstract
During pregnancy C3H mice were solely kept on a 10 or 20% liquid supply. They had free access to solids. All animals, including controls, were chloroformed on the 19th day of pregnancy and the fetuses were examined for growth regardation, intrauterine death and microscopic malformations. There was a significantly higher incidence of malformations and intrauterine deaths and significant retardation compared to the control animals. There was a clear dose-effect relation. The malformations were localized to the facial skeleton, CNS, eyes and lungs.Keywords
This publication has 11 references indexed in Scilit:
- The effects of moderate alcohol consumption during pregnancy on fetal growth and morphogenesisThe Journal of Pediatrics, 1978
- Moderate alcohol use during pregnancy and decreased infant birth weight.American Journal of Public Health, 1977
- The fetal alcohol syndrome in mice: An animal modelTeratology, 1977
- Fetal alcohol syndromeTeratology, 1976
- Adverse effects of maternal alcohol consumption on pregnancy and foetal growth in ratsNature, 1975
- The fetal alcohol syndromeTeratology, 1975
- Fetal Alcohol SyndromePublished by American Medical Association (AMA) ,1975
- OUTCOME IN OFFSPRING OF CHRONIC ALCOHOLIC WOMENThe Lancet, 1974
- Congenital Malformations in Offspring of a Chronic Alcoholic MotherPediatrics, 1974
- RECOGNITION OF THE FETAL ALCOHOL SYNDROME IN EARLY INFANCYThe Lancet, 1973