Genetic Regulatory Mechanisms at the Population Level in Man
- 13 November 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 146 (3646), 924-925
- https://doi.org/10.1126/science.146.3646.924
Abstract
The distribution of the Rhesus and ABO blood groups, thalassemia, and glucose-6-phosphate dehydrogenase deficiency in Europe and in Jewish populations argues for a regulatory mechanism at the population level which adjusts gene frequencies so that the overall genetic load is not excessive, since gene frequencies giving a high genetic load at one locus are often associated with those giving low genetic loads at other loci.Keywords
This publication has 3 references indexed in Scilit:
- Interactions within and between chromosomesJournal of Theoretical Biology, 1964
- Animal Species and EvolutionPublished by Harvard University Press ,1963
- BLOOD GROUPSBMJ, 1954