The relationship between alcohol problems and depressive symptoms is examined in a national sample of U.S. adults (N=1772) conducted in 1979. Although men were more likely to report alcohol problems while women were more likely to report depressive symptoms, the rates of overlap for both disorders were approximately equal for men and women when the total sample or current drinkers only are considered. However, when problem drinkers are analyzed separately, the percent of overlap for females was approximately twice that of males. Thus, these data support a growing body of clinical research which suggests that females with alcohol problems are more likely to report depressive symptomatology.