Maternal Phenylketonuria and Hyperphenylalaninemia
- 20 November 1980
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 303 (21), 1202-1208
- https://doi.org/10.1056/nejm198011203032104
Abstract
Since many women with phenylketonuria (PKU) will have children of their own, we were interested in ascertaining the effect of maternal PKU and hyperphenylalaninemia on the offspring of such women. We reviewed the literature on this subject and obtained additional unpublished data through an international survey. Data were collected on 524 pregnancies in 155 women; in 34 pregnancies a low-phenylalanine diet was begun after or shortly before pregnancy was established.Keywords
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