POLYRIBOSOME FORMATION AND HEMOGLOBIN SYNTHESIS
- 1 December 1963
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 50 (6), 1078-1085
- https://doi.org/10.1073/pnas.50.6.1078
Abstract
The attachment of P32-labeled 80S ribosomes to polyribosomes required energy. Studies of the kinetics and amount of de novo polypeptide chain synthesis indicated that initiation of the chain required attachment of 80S ribosomes to polyribosomes. This was confirmed by the inhibition of ribosome attachment and new chain synthesis by poly A. Completion of already started chains was correlated with ribosome detachment from the polyribosome.Keywords
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