Lysosomal membrane fragility and catabolism of cytosolic proteins: evidence for a direct relationship
- 1 March 1987
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 43 (3), 320-323
- https://doi.org/10.1007/bf01945568
Abstract
A direct relationship was established between the stability of the lysosomal membrane and an estimate of cytosolic protein catabolism, based on loss of radiolabel from prelabeled protein. Lysosomes in the lysosomally-rich digestive cells of the midgut gland of the marine mussel (Mytilus edulis) were destabilized by experimental treatment with phenanthrene.Keywords
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