LEUKEMIA CUTIS

Abstract
Since Biesiadecki1in 1876 first described the skin changes in leukemia, the subject has been of absorbing interest to dermatologists. In a review of sixteen cases of acute, or subacute, leukemia cutis, Hazen2found that the cutaneous manifestations consisted of petechiae, nodules, vesicles, bullae, papules, maculopapules, pustules, hematomas and tumors. In twenty-six cases of chronic lymphatic leukemia, he found an occurrence of pruritus, prurigo, urticaria, bronzing, vesicles, pust les, localized infiltrations, nodules and tumors. Arndt,3in a paper read before this section in 1914, prefers the name lymphadenosis to that of leukemia, and according to the blood changes, distinguishes an aleukemic form, if the blood is normal, a subleukemic form if the number of white cells is normal or very little increased but the proportion of lymphocytes is augmented, and a leukemic form when there is an absolute permanent, progressive increase of lymphocytes and the total number