Factors Affecting the Rates of Hemolysis of Mammalian Erythrocytes on Isotonic Solutions of Choline and Certain Choline Esters
- 30 November 1955
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 183 (3), 538-544
- https://doi.org/10.1152/ajplegacy.1955.183.3.538
Abstract
The rates of hemolysis of several spp. of mammalian erythrocytes (man, dog, guinea pig and rat) in isotonic solutions of acetyl choline, acetyl-[beta]-methyl choline, benzoyl choline and choline were studied. The 2 most important factors affecting these rates are the pH of the medium and erythrocyte cholinesterase activity. The acetyl choline-cholinesterase system, in addition to playing a vital role in the selective permeability of the cell membrane, may control the membrane pH.Keywords
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