A novel strategy towards the synthesis of orthogonally functionalised 4-aminoglycosides
- 21 October 2003
- journal article
- Published by Royal Society of Chemistry (RSC) in Organic & Biomolecular Chemistry
- Vol. 1 (23), 4160-4165
- https://doi.org/10.1039/b309823k
Abstract
A tethered nucleophilic substitution strategy for the stereoselective introduction of axially oriented amino functions on suitably protected gluco- and mannopyranosides is presented. The obtained oxazine is a versatile building block, which after some manipulation, could be used in the construction of highly functionalised oligosaccharides.Keywords
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