THE EFFECT OF CERTAIN FOODS ON BILE VOLUME OUTPUT RECORDED IN THE DOG BY A QUANTITATIVE METHOD

Abstract

A method is descr. wherewith consistent and reproducible results on the bile-volume output of the dog may be obtained under different exptl. conditions. The chief principle of the method is the application of continuous suction to the tube in the common bile duct. The bile-vol. output of 7 dogs on a regime of no food and no bile ranges from 6 to 10 cc. per kilo per day. On a mixed diet fed every 6 hrs. without the return of bile to the intestine, the output ranges from 13 to 18 cc. per kilo. On the same diet with the return of a standard amount of bile, it ranges from 24 to 27 cc. per kilo per day. The data obtained show that the liver under controlled conditions is as constant in its volume-output of secretions as any of the external secretory glands.