SURGICAL MANAGEMENT OF SICKLE CELL ANEMIA: THE USE OF PACKED RED BLOOD CELL TRANSFUSIONS
- 1 February 1958
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 48 (2), 399-406
- https://doi.org/10.7326/0003-4819-48-2-398
Abstract
Patients with sickle cell anemia are notably poor risks for surgery. By giving repeated transfusions of packed normal red blood cells and by maintaining a normal hemoglobin, the anemia is corrected, the bone marrow depressed, and ultimately the peripheral blood will contain predominantly red blood cells, thus diminishing the risk of surgery. The same procedure is suggested for the treatment of intractable leg ulcers and also for selected patients with sickle cell anemia and sickle cell variance in the last trimester of pregnancy.Keywords
This publication has 8 references indexed in Scilit:
- Secondary HemochromatosisBlood, 1953
- PREGNANCY AND SICKLE CELL DISEASE1953
- X-Ray and Solubility Studies of the Hæmoglobin of Sickle-Cell Anæmia PatientsNature, 1951
- EFFECT OF OXYGEN TENSION AND OF PH ON THE SICKLING AND MECHANICAL FRAGILITY OF ERYTHROCYTES FROM PATIENTS WITH SICKLE CELL ANEMIA AND THE SICKLE CELL TRAIT1951
- Studies on the Destruction of Red Blood Cells. VIII. Molecular Orientation in Sickle Cell Hemoglobin Solutions.Experimental Biology and Medicine, 1950
- EXOGENOUS HEMOCHROMATOSIS RESULTING FROM BLOOD TRANSFUSIONSBlood, 1948
- THE LIFE SPAN OF THE SICKLE CELL AND THE PATHOGENESIS OF SICKLE CELL ANEMIA1948
- SICKLE CELL ANEMIAArchives of Internal Medicine, 1927