Estrogen-Receptor Status and Outcomes of Modern Chemotherapy for Patients With Node-Positive Breast Cancer
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Open Access
- 12 April 2006
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 295 (14), 1658-1667
- https://doi.org/10.1001/jama.295.14.1658
Abstract
Great strides have been made in the treatment of early stage breast cancer. In patients with hormone-sensitive tumors, tamoxifen reduces the risk of recurrence and death by more than 30%.1 Moreover, treatment with aromatase inhibitors in place of or sequentially with tamoxifen further reduces the risk of recurrence in postmenopausal women with estrogen-receptor (ER)–positive tumors.2-4Keywords
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