Prolactin Stimulation by Thyrotropin-Releasing Hormone in a Patient with Isolated Thyrotropin Deficiency
- 9 November 1972
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 287 (19), 972-973
- https://doi.org/10.1056/nejm197211092871909
Abstract
PROLACTIN and thyrotropin (TSH) are protein hormones that appear to be produced by different cell populations of the anterior pituitary gland.1 TSH secretion is stimulated by thyrotropin-releasing hormone (TRH), a releasing factor from the hypothalamus whose effects have been well studied in man.2 Prolactin secretion, on the other hand, appears to be under tonic inhibition by a hypothalamic inhibitory factor,1 but studies in animals have suggested an additional hypothalamic stimulating factor as well.3 4 5 Recently, it has been shown in tissue culture6 and intact man7 , 8 that TRH promotes pituitary prolactin secretion in a manner qualitatively and quantitatively similar to its stimulation . . .Keywords
This publication has 8 references indexed in Scilit:
- Synthetic Thyrotropin-Releasing HormoneNew England Journal of Medicine, 1971
- INCREASED SERUM PROLACTIN AFTER ADMINISTRATION OF SYNTHETIC THYROTROPIN RELEASING HORMONE (TRH) IN MAN1Journal of Clinical Endocrinology & Metabolism, 1971
- Familial Isolated Thyrotropin Deficiency with CretinismNew England Journal of Medicine, 1971
- Prolactin and thyrotropin release in man by synthetic pyroglutamyl-histidyl-prolinamideBiochemical and Biophysical Research Communications, 1971
- Thyrotropin releasing hormone: Direct evidence for stimulation of prolactin production by pituitary cells in cultureBiochemical and Biophysical Research Communications, 1971
- Isolated deficiencies of anterior pituitary hormones. Symptoms and diagnosisJAMA, 1966
- Adenohypophysis: ProlactinAnnual Review of Physiology, 1966