Epithelial differentiation in Drosophila
- 1 August 1997
- Vol. 19 (8), 673-682
- https://doi.org/10.1002/bies.950190807
Abstract
Our understanding of epithelial development in Drosophila has been greatly improved in recent years. Two key regulators of epithelial polarity, Crumbs and DE‐cadherin, have been studied at the genetic and molecular levels and a number of additional genes are being analyzed that contribute to the differentiation of epithelial cell structure. Epithelial architecture has a profound influence on morphogenetic movements, patterning and cell‐type determination. The combination of embryological and genetic/molecular tools in Drosophila will help us to elucidate the complex events that determine epithelial cell structure and how they relate to morphogenesis and other developmental processes.Keywords
This publication has 74 references indexed in Scilit:
- Drosophila α-Catenin and E-cadherin Bind to Distinct Regions of Drosophila ArmadilloJournal of Biological Chemistry, 1996
- Armadillo is required for adherens junction assembly, cell polarity, and morphogenesis during Drosophila embryogenesis.The Journal of cell biology, 1996
- Cell signalling: MAGUK magicCurrent Biology, 1996
- Origins of Cell PolarityCell, 1996
- Cell adhesion and signal transduction: the Armadillo connectionTrends in Cell Biology, 1995
- Localization of DER and the pattern of cell divisions in wild-type and Ellipse eye imaginal discsDevelopmental Biology, 1992
- Phenotypic and developmental analysis of mutations at thecrumbs locus, a gene required for the development of epithelia inDrosophila melanogasterWilhelm Roux' Archiv für Entwicklungsmechanik der Organismen, 1990
- Centrosome splitting during nuclear elongation in the Drosophila embryoExperimental Cell Research, 1988
- F-actin distribution during the cellularization of the embryo visualized with FL-phalloidinExperimental Cell Research, 1983
- Nuclear elongation and cytokinesis in Drosophila montanaDevelopmental Biology, 1971