The Prephase Accelerator. Present Status
- 1 January 1961
- journal article
- research article
- Published by Georg Thieme Verlag KG in Thrombosis and Haemostasis
- Vol. 6 (02), 254-260
- https://doi.org/10.1055/s-0038-1654558
Abstract
The properties of the prephase accelerator (PPA) are indicated as well as its differentiation from other known clotting factors. PPA is either a reaction product or a degratation product. For its normal formation genuine factor IX, PTA and ? Hageman factor are necessary. The one-stage quantitative assay method for factor “IX” does not determine the factor lacking in haemophilia B. This method gives a measure of PPA. Some practical observations are made concerning the value of the one-stage assay method for factor “IX” and of the thromboplastin generation test for the diagnosis of haemophilia B.Keywords
This publication has 4 references indexed in Scilit:
- Purification of Factor IX or its Precursor Isolation of a Hageman-PTA FractionThrombosis and Haemostasis, 1961
- The Relation between a Naturally Occuring Inhibitor and Prothrombin in Intermediate Product I FormationThrombosis and Haemostasis, 1960
- The Formation of Intermediate Product I in a Purified System The Role of Factor IX or of its Precursor and of a Hageman Factor-PTA FractionThrombosis and Haemostasis, 1960
- Separation of Coagulation Factors by Means of Starch Gel ElectrophoresisThrombosis and Haemostasis, 1960