Adhesiveness of platelets and leukocytes during acute exsanguination

Abstract

Dogs were subjected to acute exsanguination during which their blood was tested for adhesive or aggregated blood elements by passing the blood through a microfilter with multiple precise pores 20 µ sq. During the latter half of exsanguination the leukocytes and platelets became progressively more adhesive, but significant aggregation was not observed. This was attended by a rapid fall in mean blood pressure. Treating blood containing adhesive platelets and leukocytes with Pyrex glass wool removed significant numbers of these adhesive elements from the blood.