Risk factors of recurrent angina pectoris and of non-fatal myocardial infarction after coronary artery bypass surgery

Abstract
The long-term results of 1025 patients, 912 men and 113 women,undergoing coronary artery bypass grafting (CABG) at the CardiovascularUnit of Rikshospitalet, Oslo, between 1982 and 1986, were analyzed onfactors associated with the return of angina pectoris and of non-fatal postCABG myocardial infarction. The closing date was 1st January 1993, with amean follow-up time of 7.4 years. Recurrent angina pectoris was experiencedby 118 (11.6%) patients and 102 (10%) patients experienced non-fatal postCABG myocardial infarction during the observation period. Altogether 30possible risk factors were analyzed. The cumulative incidence of recurrentangina was initially low after operation, followed by a rise after 4 years.One, 5 and 10 years after the operation, survival free from angina rateswere 97.8%, 91.8% and 80.6%, respectively. The cumulative incidence of postCABG myocardial infarction was also low initially, followed by a rise after4 years. The survival free of non-fatal post CABG myocardial infarctionrate was 98.9%, 96% and 83.5%, at 1, 5 and 10 years after surgery,respectively. The incremental risk factor of recurrent angina pectoris washypertension. The independent risk factors of non-fatal post CABGmyocardial infarction were hypertension and preoperative stenosis of theleft-sided, versus right-sided, coronary arteries. The study emphasizes thefavorable effect of coronary bypass surgery on the functional outcome inpatients with symptomatic coronary artery disease.