FOLLICLE-STIMULATING HORMONE AND LUTEINIZING HORMONE IN SERUM DURING THE MENSTRUAL CYCLE DETERMINED BY RADIOIMMUNOASSAY

Abstract

The serum levels of FSH and LH were determined in 11 normal menstrual cycles by radioimmunoassay. The results of LH assay demonstrated a consistent pattern with a sharp 3 to 4 fold increase occurring on the average 13.9 days before the next menses. The changes in FSH levels during the cycle were neither as marked nor as consistent. Three distinct patterns seemed to emerge. However, the mean levels of FSH from the 11 cycles demonstrated a significant high level 12 days before, a low level 1 day before and another rise 1 day after the midcycle peak of LH.