Under the heading, "An Autograph History of a Case of Addison's Disease," the late Dr. A. L. Muirhead1gave an unusually interesting description of the clinical course of his own illness. In this report we find a professor of pharmacology investigating and recording the subjective and objective results of treatment on himself, and the effects of drugs on the course of Addison's disease, from which he suffered and eventually died. I will record the course of events subsequent to his report, which covered his illness until December, 1920. CLINICAL COURSE Dr. Muirhead left the Mayo Clinic, Aug. 11, 1920, and for several months continued to improve. The pigmentation had almost disappeared, and he was able to resume his work as professor of pharmacology in Creighton Medical School. Improvement continued until Jan. 25, 1921, when there developed a gastric upset, loss of appetite, abdominal discomfort and weakness, accredited by Dr.