Mapping Cu(II) Binding Sites in Prion Proteins by Diethyl Pyrocarbonate Modification and Matrix-assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) Mass Spectrometric Footprinting
Open Access
- 1 January 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (3), 1981-1990
- https://doi.org/10.1074/jbc.m108744200
Abstract
No abstract availableKeywords
This publication has 60 references indexed in Scilit:
- XAFS study of the high-affinity copper-binding site of human PrP 91–231 and its low-resolution structure in solution 1 1Edited by I. A. WilsonJournal of Molecular Biology, 2001
- Copper(II)-induced Conformational Changes and Protease Resistance in Recombinant and Cellular PrPJournal of Biological Chemistry, 2000
- Diethyl Pyrocarbonate Modification Abolishes Fast Electron Accepting Ability of Cytochrome b561 from Ascorbate but Does Not Influence Electron Donation to Monodehydroascorbate Radical: Identification of the Modification Sites by Mass Spectrometric AnalysisBiochemistry, 2000
- A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoformJournal of Molecular Biology, 1997
- Selective Biochemical Modification of Functional Residues in Recombinant Human Macrophage Colony-Stimulating Factor β (rhM-CSF β): Identification by Mass SpectrometryBiochemistry, 1996
- Copper Binding to the N-Terminal Tandem Repeat Region of Mammalian and Avian Prion Protein: Structural Studies Using Synthetic PeptidesBiochemical and Biophysical Research Communications, 1995
- Copper Binding to the N-Terminal Tandem Repeat Regions of Mammalian and Avian Prion ProteinBiochemical and Biophysical Research Communications, 1995
- Carbethoxylation of coordinated histidine by diethylpyrocarbonateJournal of Inorganic Biochemistry, 1993
- Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltonsAnalytical Chemistry, 1988
- Reversible Chemical Modification of the Scrapie AgentScience, 1981