INTRATHECAL TUBERCULIN IN DISSEMINATED SCLEROSIS: THE IMMUNOLOGICAL ASPECTS

Abstract

A study of the intradermal and intrathecal response to tuberculin (PPD) in 248 cases of disseminated sclerosis has shown that the immunological disorder associated with this disease is of the delayed type of hypersensitivity. It affects the body as a whole and not only the central nervous system. Disseminated sclerosis is classified as an auto-immune disease. On the basis of pathogenesis the hypersensitivity may represent a defence mechanism rather than a process related to the disorder.