5-Iodo-2′-Deoxyuridine: Relation of Structure to Its Antiviral Activity
- 12 June 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 144 (3624), 1348-1350
- https://doi.org/10.1126/science.144.3624.1348
Abstract
The crystal and molecular structure of 5-iodo-2'-deoxyuridine has been determined by x-ray diflraction methods. The most interesting feature of the structure is an unusually short intermolecular distance between the iodine and oxygen of a carbonyl group; this type of bonding may be the molecular basis for the antiviral activity. a different crystal structure.Keywords
This publication has 3 references indexed in Scilit:
- Specific Inhibition of Replication of Animal VirusesScience, 1963
- IDU Therapy of Herpes SimplexArchives of Ophthalmology (1950), 1962
- Direct structural evidence for weak charge-transfer bonds in solids containing chemically saturated moleculesQuarterly Reviews, Chemical Society, 1962