Immunological aspects of psoriasis.

Abstract
Sixty patients with psoriasis were studied for quantitative estimation of serum immunoglobulin A [IgA], IgG and IgM (60 cases), IgE (43 cases), salivary IgA (28 cases) and anti-IgG factors in the serum (40 cases). All the data were statistically compared to a large control group (300 subjects). The results show an increase of the serum IgG and IgA means, an increase of salivary IgA which is correlated with the serum IgA, an increase of IgE levels in some patients and the presence of anti-IgG activity in the serum of 45% of patients with psoriasis. These findings are statistically significant when compared to controls. These data suggest auto-immune processes in psoriasis.