Anaemia of Felty's Syndrome
Open Access
- 1 July 1964
- journal article
- research article
- Published by BMJ in Annals Of The Rheumatic Diseases
- Vol. 23 (4), 267-271
- https://doi.org/10.1136/ard.23.4.267
Abstract
The mechanism of the anemia in 4 cases of Felty''s syndrome was studied, using radioactive chromium (Cr51) as a red cell label before and after splenectomy. In 1 case Fe utilization was also measured, using radioactive iron (Fe59) before and after splenectomy. It was concluded that the anemia is mainly due to hemolysis. There was evidence of Increased splenic sequestration of erythrocytes and the anemia was rectified in all patients by splenectomy. Radioiron studies confirmed an inadequate iron utilization for hemoglobin synthesis and this was not improved by splenectomy. Splenectomy corrected the leucopenia present in each case and also the thrombocytopenia which occurred in 2 of them.This publication has 15 references indexed in Scilit:
- The Nature of Anaemia in Rheumatoid Arthritis: V. Red Cell Survival measured by Radioactive ChromiumAnnals Of The Rheumatic Diseases, 1961
- [Critical study of Felty's syndrome].1959
- DIAGNOSTIC criteria for rheumatoid arthritis: 1958 revision by a committee of the American Rheumatism Association.1959
- THE RELATIONSHIP OF TOTAL RED CELL MASS TO LEAN BODY MASS IN MAN1957
- CLINICAL DETERMINATION OF THE SITES OF RED CELL SEQUESTRATION IN HEMOLYTIC ANEMIAS 1Journal of Clinical Investigation, 1956
- Felty's syndrome.1956
- The Anemia of Rheumatoid ArthritisMedical Clinics of North America, 1955
- The Use of the Isotope 51Cr as a Label for Red CellsBritish Journal of Haematology, 1955
- Splenic Neutropenia in the Felty SyndromeBlood, 1954
- PRIMARY THROMBOCYTOPENIC PURPURA AND ACQUIRED HEMOLYTIC ANEMIAA.M.A. Archives of Internal Medicine, 1951