Immunologic Comparison of Different Laboratory Lines of the Lansing Strain of Poliomyelitis Virus

Abstract

An immunologic comparison was made of three different laboratory lines of the Lansing strain of poliomyelitis virus. The three preparations studied had been from the 83rd, 206th and 393rd mouse passages respectively. By the methods employed the three were indistinguishable. A fourth preparation that had been adapted recently to monkeys could not be studied in mice because of the low infectious titer of the virus pool. It was studied, nevertheless, and the findings (10) are that it too is indistinguishable antigenically from the other three.