Oxidative degradation of L-ascorbic acid acetals to 2′,3′-dideoxy-3′-oxaribofuranosides. Synthesis of enantiomerically pure 2′,3′-dideoxy-3′-oxacytidine stereoisomers as potential antiviral agents
- 10 November 1992
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 33 (46), 6949-6952
- https://doi.org/10.1016/s0040-4039(00)60903-6
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Asymmetric synthesis of 1,3-dioxolane-pyrimidine nucleosides and their anti-HIV activity.Journal of Medicinal Chemistry, 1992
- The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitroAntimicrobial Agents and Chemotherapy, 1992
- Asymmetric synthesis of enantiomerically pure (−)-(1′R,4′R)-dioxolane-thymine and its anti-HIV activity.Tetrahedron Letters, 1991
- (±)-Dioxolane-T ((±)-1-[(2β,4β)-2-(hydroxymethyl)-4-dioxolanyl]thymine): A new 2′,3′-dideoxynucleoside prototype within vitro activity against HIVTetrahedron Letters, 1989
- The chemistry of L-ascorbic and D-isoascorbic acids. 1. The preparation of chiral butanetriols and -tetrolsThe Journal of Organic Chemistry, 1988
- 3'-Substituted 2',3'-dideoxynucleoside analogs as potential anti-HIV (HTLV-III/LAV) agentsJournal of Medicinal Chemistry, 1987
- Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.Proceedings of the National Academy of Sciences, 1986
- 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.Proceedings of the National Academy of Sciences, 1985
- Practical enantiospecific syntheses of (+) erythro-9- (2s-hydroxy-3r-nonyl) adenine.Tetrahedron Letters, 1984
- Total synthesis of (R)-glycerol acetonide and the antiepileptic and hypotensive drug (-)-.gamma.-amino-.beta.-hydroxybutyric acid (GABOB): use of vitamin C as a chiral starting materialJournal of the American Chemical Society, 1980