Early‐eye morphogenesis in the zebrafish, Brachydanio rerio
- 22 June 1994
- journal article
- research article
- Published by Wiley in Journal of Comparative Neurology
- Vol. 344 (4), 532-542
- https://doi.org/10.1002/cne.903440404
Abstract
Early eye morphogenesis in the zebrafish between 12 and 36 hours postfertilization was studied by light- and scanning electron microscopy. Overall, early eye morphogenesis in the zebrafish is similar to that vertebrates even thought the optic primordia evaginate from the forebrain as solid masses of cells. After initial evagination 6–7 somite stage [SS], the optic primordia take on a wing-like shape (8–9 SS). Subsequently, they bend ventrally and rotate slighlty in an anterior direction (10–12 SS). These changes serve to bring the primordia from a horizontal to a more Vertical orientation in relation to the embryonic neural axis. Invagination commences from the center of each primordium (14 SS) and progresses symmetrically out towards the periphery (14–20 SS). The choroid fissure forms by an involution along the anterior region of the eyecup (18–20 SS). By 24 hours postfertilization (pf), the eyecups are well formed. Between 24 and 36 hours pf, the eyes rotate further in relation to the axis of the embryo, and this repositions the choroid fissue to a typical ventral location by 36 hours pf. Because of the two rotations of the eye during early morphogenesis, particularly the later one, the anterior-posterior orientation of the emerging optic primordium ultimately becomes the ventral-dorsal axis of the completed eyecup.Keywords
This publication has 22 references indexed in Scilit:
- Neurulation in the anterior trunk region of the zebrafish Brachydanio rerioWilhelm Roux' Archiv für Entwicklungsmechanik der Organismen, 1993
- Patterning the Brain of the Zebrafish EmbryoAnnual Review of Neuroscience, 1993
- Comparative analysis of Pax-2 protein distributions during neurulation in mice and zebrafishMechanisms of Development, 1992
- Zebrafish embryology and neural developmentCurrent Opinion in Cell Biology, 1991
- Retinoic acid causes an anteroposterior transformation in the developing central nervous systemNature, 1989
- Analysis of tissue interactions in chick eye morphogenesis using cytochalasin BExperimental Eye Research, 1982
- Microfilament patterns in the developing chick eye: Their role in invaginationsExperimental Eye Research, 1982
- Cephalic flexure formation in the chick embryoJournal of Experimental Zoology, 1981
- Ontogeny of the retina and optic nerve in Xenopus laevis. I. Stages in the early development of the retinaJournal of Comparative Neurology, 1980
- The prenatal development of the mouse eyeThe Anatomical Record, 1970