In the treatment of sarcoma of the uveal tract the main issue at the moment is: Must an exenteration of the orbit be done at the outset in every case, or may one, in a desire to avoid further mutilation, first enucleate the eye, and rest the decision of a subsequent exenteration on the conditions discovered during the caurse of the enucleation and on the observations of the pathologist? What we wish to do in the general interest of ophthalmic practice is to set forth the elements of the problem and to indicate what the treatment of uveal sarcoma may be in the present state of knowledge. As the indications for an operation can be assessed only in the light of the conditions it is designed to meet, we shall first consider the alternative procedures in relation to the two main phases of malignant spread. That general metastases are necessarily