BINDING OF PHYTOHEMAGGLUTININ TO SERUM SUBSTANCES AND INHIBITION OF LYMPHOCYTE-TRANSFORMATION IN HODGKINS-DISEASE
- 1 January 1976
- journal article
- research article
- Vol. 26 (3), 520-527
Abstract
Serum from 11 of 54 patients with Hodgkin''s disease inhibited phytohemagglutinin (PHA) stimulation of autologous and homologous lymphocytes. The inhibitory effect resided in the macromolecular fraction of these sera. PHA bound to serum substances in inhibitory sera and the degree of PHA binding in the macromolecular fraction correlated directly with the extent of inhibition.This publication has 17 references indexed in Scilit:
- Recent immunological findins in Hodgkin's disease.1973
- Studies on pregnancy-associated globulin.1973
- The effects of human serum fractions on phytohemagglutinin- and concanavalin A-stimulated human lymphocyte culturesCellular Immunology, 1972
- REDUCED LYMPHOCYTE TRANSFORMATION IN BREAST CANCERThe Lancet, 1971
- LYMPHOCYTE RESPONSE TO P.H.A. IN PATIENTS WITH NON-LYMPHOID TUMOURSThe Lancet, 1970
- REDUCED LYMPHOCYTE TRANSFORMATION DUE TO A PLASMA FACTOR IN PATIENTS WITH ACTIVE SYPHILISThe Lancet, 1969
- Lymphocyte response to phytohemagglutinin in Hodgkin's disease, lymphatic leukemia and lymphosarcomaCancer, 1966
- Impaired in Vitro Lymphocyte Transformation in Hodgkin's DiseaseNew England Journal of Medicine, 1965
- THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITYBiochemical Journal, 1963
- Effect of Phytohæmagglutinin on Human Serum and Cell ProteinsNature, 1962