INHIBITION OF THROMBIN AND TRYPSIN BY TRIPEPTIDE ALDEHYDES
- 1 October 1978
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 12 (4), 217-221
- https://doi.org/10.1111/j.1399-3011.1978.tb02889.x
Abstract
Inhibitory effects of certain tripeptide aldehydes on [bovine] thrombin and trypsin were strongly substrate-dependent. These compounds should therefore be considered as inhibitors of the particular proteolytic reaction for which they had been designed rather than real enzyme inhibitors, i.e., protein or polypeptide proteinase inhibitors of natural origin.Keywords
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