Improvement in experimental vascular graft patency by controlled defibrinogenation
- 1 January 1977
- journal article
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 64 (1), 28-30
- https://doi.org/10.1002/bjs.1800640107
Abstract
A sensitive animal model was used to investigate treatment designed to improve vascular graft patency. A Dacron graft was inserted into the infrarenal vena cava of 30 rabbits. Half were treated with subcutaneous Arvin for 28 days after operation. This produced a significant lowering of the postoperative plasma fibrinogen. The patency rate of the grafts in the treated rabbits was significantly greater than in the control rabbits.Keywords
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