Phosphoglucoisomerase-catalyzed interconversion of hexose-phosphates
- 1 August 1989
- journal article
- research article
- Published by Springer Nature in Molecular and Cellular Biochemistry
- Vol. 89 (1), 57-67
- https://doi.org/10.1007/bf00228280
Abstract
The rate of conversion of D-glucose 6-phosphate to D-fructose 6-phosphate as catalyzed by yeast phosphoglucoisomerase is about fourfold lower when 3H, rather than 1H, is present on the C2 of D-glucose 6-phosphate. This difference appears to be due mainly to a change in maximal velocity, rather than affinity. Phosphoglucoisomerase also distinguishes between 1H and 3H in terms of either their intramolecular transfer from C2 to C1 or their incorporation from water on the C1 of D-fructose 6-phosphate.Keywords
This publication has 7 references indexed in Scilit:
- Underestimation of d-glucose phosphorylation as measured by 3H2O production from d-[2-3H]glucoseBiochemical Medicine and Metabolic Biology, 1988
- Anomeric Specificity of Mammalian HexokinaseArchives Internationales de Physiologie et de Biochimie, 1986
- Glucose phosphorylation, glucose-6-phosphatase, and recycling in rat hepatocytesJournal of Biological Chemistry, 1978
- Cytochalasin B-Induced Impairment of Glucose Metabolism in Islets of LangerhansEndocrinology, 1976
- The Metabolism of Glucose-2-T by Adipose TissueJournal of Biological Chemistry, 1969
- Intramolecular Hydrogen Transfer in the Phosphoglucose Isomerase ReactionJournal of Biological Chemistry, 1961
- USE OF KINETIC ISOTOPE EFFECTS IN STUDY OF METABOLIC CONTROL .1. DEGRADATION OF GLUCOSE-1-D BY HEXOSEMONOPHOSPHATE PATHWAY1961