Gastrin Injected into the Lateral Hypothalamus Stimulates Secretion of Gastric Acid in Rats
- 5 September 1980
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 209 (4461), 1142-1143
- https://doi.org/10.1126/science.7403876
Abstract
Intrahypothalamic injections of 100 picomoles of pentagastrin or natural gastrin promptly increased secretion of gastric acid in conscious rats. The response was blocked by atropine and by vagotomy. The same doses, injected intravenously or into other forebrain sites, did not increase secretion, nor did intrahypothalamic injections of other peptides common to the gut and brain.Keywords
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