Principles and Techniques of Mixed Radiation Dosimetry: Application to Acute Lethality Studies of Mice with the Cyclotron

Abstract

It is shown that for a typical biological experiment, in which a cyclotron with an internal target was used as a radiation source, the fast neutron dose as measured with a proportional counter dosimeter and threshold detectors agreed within 10%. Furthermore, the readings of the Failla-Rossi tissue-equivalent chamber, when corrected for gamma-ray response by exposing photographic film in the Bureau of Standards film packet, gave approximately the same neutron dose. The threshold detector method of fast neutron dosimetry had the important advantage that the dose distribution versus energy allows a simple calculation of the distribution of absorbed energy versus linear energy transfers to be made.